Rubbed with a smoky, chipotle brown sugar rub, this Smokey Brown Sugar Crusted Pork Tenderloin is grilled to juicy perfection. A squeeze of fresh lime juice perfectly compliments each bite of sticky, crusty and perfectly moist lean pork.

Pork Tenderloin is a great weeknight grill choice. I feel like pork tenderloin (and pork loin) is vastly underused. It can be incredibly juicy, tender, takes marinades and rubs well, is low in fat and therefore a health conscience choice, and relatively inexpensive per pound.
What is pork Tenderloin? Pork Tenderloin, not to be confused with Pork Loin, is also called pork fillet or Gentleman’s Cut and is a long thin cut of pork. The tenderloin refers to the psoas major muscle along the central spine portion, ventral to the lumbar vertebrae. This is the most tender part of the animal, because these muscles are used for posture, rather than locomotion.
How to make Smokey Brown Sugar Crusted Pork Tenderloin
Begin by combining brown sugar with chipotle chili powder, smoked paprika, onion powder, garlic powder, salt, and cumin. Stir everything together in a small mixing bowl and then rub the mixture all over the pork tenderloin(s).
Smaller pork tenderloins are commonly sold two to a package, while larger ones can be sold individually. Choose pork tenderloins labeled fresh, minimally processed, and with-out preservatives.
Let the rub covered pork sit at room temperature for 20-30 minutes while the grill preheats to a medium high heat.
Rub the grill grates with oil, and then place the pork tenderloin(s) directly over the flame. Rotate the tenderloin every 2-3 minutes, searing and caramelizing the outside.
What temperature should I cook pork to?
The National Pork Board recommends cooking pork tenderloin to an internal temperature of 145 degrees Fahrenheit. My preference on pork tenderloin is just a trace of pink. All of the juiciness, without being too rare. This is reached by cooking the tenderloins to 140 degrees and then the meat will continue to cook up as it rests for 10 minutes before slicing.
After the outside edges are well browned and caramelized, move the pork tenderloins to an indirect heat (not directly over the flame), and continue to cook the pork, with the lid closed until the internal temperature reaches 140 degrees Fahrenheit. Depending on the size of the pork tenderloins, this can be 5 minutes to another 20 minutes. A meat thermometer is a necessary tool for this.
Let the pork rest for 10 minutes before slicing and serving with fresh lime wedges. The bright citrus of the lime juice squeezed on the smokey, sweet pork is the perfect flavor combination.
What should I serve with my Grilled Pork Tenderloin?
A few of my favorite sides include
- GRILLED TRIPLE BERRY CRISP IN A CAST IRON SKILLET
- EASY GRILLED CHEESY POTATO CASSEROLE
- PICKLED CUCUMBER AND RED ONION SALAD
Make sure to check out the video below where my favorite sous chef and I demonstrate these!
Can I make Smoky Brown Sugar Crusted Pork Tenderloin in the oven?
Absolutely! Roast in a 400 degree oven in a lightly greased baking dish for 20-35 minutes depending on the size of the pork tenderloin(s) until the center reaches 140 degrees and the outside is golden and caramelized. Let the pork rest for 10 minutes before slicing.
Can I use this Smoky Brown Sugar Rub on other types of meat?
Yes! This is the same rub I use on Sticky Asian Baked Pork Ribs and Sticky Asian Grilled Chicken . I’ve used it when roasting a pork shoulder, smoking a chuck roast, and salmon as well with great results. Cooking times and preparation vary depending on the protein choice.
This recipe is great for larger gatherings as well. The rub can easily be doubled or tripled for multiple tenderloins.

Do you love grilling as much as I do? Check out my other favorites:
- GRILLED TRIPLE BERRY CRISP IN A CAST IRON SKILLET
- STICKY ASIAN GRILLED CHICKEN THIGHS
- BOURBON BACON GRILLED BAKED BEANS
- BOURBON BACON HAM AND PINEAPPLE KABOBS ON THE GRILL
- GRILLED TERIYAKI STEAK
- GRILLED BANG BANG SHRIMP
- HERB BUTTER SPATCHCOCK CHICKEN AND ROASTED VEGETABLES
- EASY GRILLED PARMESAN ASPARAGUS
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Smoky Brown Sugar Crusted Pork Tenderloin
Ingredients
- 1.5 pounds pork tenderloin
- 2 limes – cut into wedges
Brown Sugar Chipotle Spice Rub
- 1/2 cup brown sugar
- 1/2 teaspoon kosher salt – course
- 1/2 teaspoon chipotle chili powder
- 1/2 teaspoon smoked paprika
- 1/2 teaspoon onion powder
- 1/2 teaspoon garlic powder
- 1/4 teaspoon cumin
Instructions
- Preheat barbecue grill to a medium-high heat and then oil grill grates.
- Combine Brown Sugar Chipotle Spice Rub ingredients together in a small bowl.
- Rub pork tenderloin(s) with spice rub.
- Place pork tenderloins directly over barbecue grill flame and cook 2-3 minutes per side, rotating tenderloins to caramelize the outside of the pork, but not to the point of burning.
- Move pork tenderloins to in-direct heat and continue to cook for 8-10 minutes until the internal temperature reaches 140-145 degrees Fahrenheit.
- Let the meat rest for 10 minutes before slicing.
- Serve with lime wedges for squeezing if desired.
Video
Notes
Oven Directions: Roast in a 400 degree oven in a lightly greased baking dish for 20-35 minutes depending on the size of the pork tenderloin(s) until the center reaches 140 degrees and the outside is golden and caramelized. Let the pork rest for 10 minutes before slicing.
Nutrition
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Mother, Gardener, Book Devourer, and Food Obsessor. I love being inspired with fresh, seasonal ingredients and relish every opportunity to elevate my home cooking. Join me!
Ashley
This recipe was so good! We didn’t even use the limes. Would definitely use this rub again. Thanks!
Jennifer Grissom
Thanks Ashley! I’m so happy you enjoyed it!
Kathy
Had the whole family for Jan. birthdays.. doubled this recipe for 2 pork loins to make BBQ…they loved it!! Next time I will probably triple it for 2 pork loins to give it even more flavor!! Thank you so much!
Jennifer Grissom
That’s awesome Kathy! Thanks for letting me know how much they loved it!